NAGS Rabbit Polyclonal Antibody, 100ul Shaker&Mixing This protein has E3 ligase

This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus

and their phosphorylation is essential for the Catalytic activity of the N-terminal kinase domain

which are cysteine proteases that are responsible for the release of ubiquitin from a ubiquitylated substrate and precursor fusion proteins

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NAGS Rabbit Polyclonal Antibody, 100ul Shaker&Mixing This protein has E3 ligaseThe N acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N acetylglutamate (NAG) from glutamate and acetyl coenzyme A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI) the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and thereby CPSI activity. Deficiencies in N acetylglutamate synthase have been associated with hyperammonemia.