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GNE-477 - CAS# 1032754-81-6 Catalog No.:M10487-2 Suplatast tosilate inhibits mouse and

GNE-477 - CAS# 1032754-81-6 Catalog No.:M10487-2 Suplatast tosilate inhibits mouse and

Name: GNE-477 - CAS# 1032754-81-6 Catalog No.:M10487-2 Suplatast tosilate inhibits mouse and
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GNE-477 - CAS# 1032754-81-6 Catalog No.:M10487-2 Suplatast tosilate inhibits mouse andGNE 477 is a dual inhibitor of PI3K (IC50 = 4 nM for PI3K) and mTOR (apparent Ki = 21 nM). Product information CAS Number: 1032754 81 6 Molecular Weight: 504. 63 Formula: C21H28N8O3S2 Synonym: GNE477 GNE 477 Chemical Name: 5 {6 [(4 methanesulfonylpiperazin 1 yl)methyl] 7 methyl 4 (morpholin 4 yl)thieno[3,2 d]pyrimidin 2 yl}pyrimidin 2 amine Smiles: CC1C2=NC(=NC(=C2SC=1CN1CCN(CC1)S(C)(=O)=O)N1CCOCC1)C1=CN=C(N)N=C1 InChiKey: AKKCGLXULFRAET UHFFFAOYSA N

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Description

Suplatast tosilate inhibits mouse and human cytokine production

(http://en

1038/nchembio

WZ4003 inhibits the phosphorylation of the only well-characterized substrate

Rybczynska A

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