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A PbGST 3D structural homology model was generated by comparative modeling with the PfGST (PDB code 1Q4J) as a template (Figure 2B)

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Furthermore, the increased solubility of CsA owing to the formation of a ternary complex with SBE--CD and SP played a pivotal role in increasing the availability of CsA at the ocular surface for absorption by acting as a carrier

Overall, the rapid progress in the understanding and development of ACPs as anticancer agents brings hope for improved cancer treatments with enhanced selectivity, reduced toxicity, and increased efficacy