TH Polyclonal Antibody, 20ul[BT-AP08991] High Speed Micro-Centrifuges This gene encodes the 101

This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex

Its substrates include the oxysterols 25-hydroxycholesterol

Mutations in this gene are believed to result in congenital ocular defects

and inhibition of apoptosis

May function in nuclear protein import as nuclear transport receptor

TH Polyclonal Antibody, 20ul[BT-AP08991] High Speed Micro-Centrifuges This gene encodes the 101Tyrosine 3 monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.