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The mechanism involves enhanced cyclic adenosine monophosphate (cAMP) production and direct pituitary somatotroph cell activation

It has been shown to reverse physiological anomalies commonly associated with ASD, including increased oxidative stress, mitochondrial dysfunction, and neuroinflammation

Oral Oncology , 48 , 122735

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Luteolin selectively inhibits the type of O-glycosylation (Mucin-type O -glycosylation) involved in the formation of amyloid- .[ref] Animal studies show luteolin inhibits neuroinflammation by controlling microglia activation.[ref] In a mouse study of Alzheimers, luteolin protects against amyloid memory dysfunction and also increases levels of endogenous antioxidants, including Mn-SOD, Cu/Zn-SOD, and glutathione

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