Glucosidase II Alpha Polyclonal Antibody, 50ul Liquid Handling ＆Storage AKR1C3 shares high sequence identity

AKR1C3 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14

Like its related family member

Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap

this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development

and may be involved in cancer

Glucosidase II Alpha Polyclonal Antibody, 50ul Liquid Handling ＆Storage AKR1C3 shares high sequence identityGANAB encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal dominant polycystic