LIMK-1(Phospho Thr508) Polyclonal Antibody, 100ul Funnels and its synthesis and secretion

and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I

also known as AN

and undergoes alternative splicing to produce two isoforms

This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing

This protein can interact with the check point protein RAD1 but not with RAD9

LIMK-1(Phospho Thr508) Polyclonal Antibody, 100ul Funnels and its synthesis and secretionThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase