Syk Polyclonal Antibody, 100ul[BT-AP08702] Modification Enzymes A multitude of mutant alleles

A multitude of mutant alleles with phenotypic effects have been identified

Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors

The TPD52 gene maps to chromosome 8q21

The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding

and passed explosion-proof test

Syk Polyclonal Antibody, 100ul[BT-AP08702] Modification Enzymes A multitude of mutant allelesSYK encodes a member of the family of non receptor type Tyr protein kinases. Tyrosine protein kinase SYK is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas.