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Clinical data insights: In a large placebo-controlled trial, tesamorelin raised IGF-1 by 181% on average, but about 5% of participants discontinued due to adverse events, most commonly musculoskeletal pain and injection-site irritation (Falutz et al., NEJM )

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Instead, L-Carnitine plays a natural role in the way the body uses fat for fuel

But there were performance benefits too (see figure 2): During 30 minutes of exercise at 50% VO2max (mild intensity), the carnitine group were using 50% less glycogen during exercise ( ie more from fat oxidation) by the 24th week of loading compared to the control group