Triapine - CAS# 143621-35-6 0264 01-10 µM) inhibits cell proliferation

01-10 µM) inhibits cell proliferation in a dose- and time-dependent manner

30 μM)-induced protective effects on fibroblasts[2]

also known as SM04690

ISRIB potently reverses the effects of eIF2α phosphorylation (IC50=5 nM)

RIPK2 inhibitor 1

Triapine - CAS# 143621-35-6 0264 01-10 µM) inhibits cell proliferationTriapine, also known as 3 AP and OCX 191, CAS No. 143621 35 6, is a synthetic heterocyclic carboxaldehyde thiosemicarbazone with potential antineoplastic activity. Triapine inhibits the enzyme ribonucleotide reductase, resulting in the inhibition of the conversion of ribonucleoside diphosphates to deoxyribonucleotides necessary for DNA synthesis. This agent has been shown to inhibit tumor growth in vitro. Product information CAS Number: 143621 35 6