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Crystallization of organic glasses: effects of polymer additives on bulk and surface crystal growth in amorphous nifedipine

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European urology

40 Within this cycle, glutamine-derived carbon is converted to oxaloacetate and then to malate, which exits the mitochondria and is decarboxylated to NADPH and pyruvate by cytosolic malic enzyme (ME1), ultimately yielding lactate

However, the literature does not yet provide a fully resolved primary molecular target, a unified causal mechanism, or sufficient controlled human evidence to support conclusions about therapeutic use