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TB-500 has a distinct amino acid segment [(17)LKKTETQ(23)] which is hypothesized to be responsible for actin binding and potentially enhancing cellular motility

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299 Bioactivity screening showed 132 displays activity against the pathogenic bacterium Mycobacterium tuberculosis

It is important to differentiate Wilsons disease from other conditions, which may include: Menkes disease : an X-linked recessive disorder caused by mutations in the ATP7A gene, resulting in a copper deficiency 7 Aceruloplasminaemia : characterised by abnormal iron accumulation in the brain and other organs due to mutations in the ceruloplasmin (CP) gene 8 Liver diseases of different aetiology: stigmata of acute or chronic liver failure may indicate alternative liver conditions such as autoimmune hepatitis , alcohol-related liver disease or non-alcoholic fatty liver disease

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