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Start your intake How Semaglutide Causes Bloating and Digestive Discomfort Semaglutide works by activating GLP-1 receptors in your brain and gut, which signals fullness and reduces hunger

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In the STEP 1 clinical trial (using Wegovy), participants who discontinued semaglutide after one year of treatment regained roughly two-thirds of their initial weight loss over the following year

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