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MCAD Polyclonal Antibody, 100ul Sample Library Tubes Promotes endocytosis| possesses opsonic properties

SKU: 74012669570

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MCAD Polyclonal Antibody, 100ul Sample Library Tubes Promotes endocytosis| possesses opsonic propertiesACADM encodes the medium chain specific (C4 to C12 straight chain) acyl Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta oxidation pathway. Defects in this gene cause medium chain acyl CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants

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Description

Promotes endocytosis| possesses opsonic properties and influences the mineral phase of bone

Together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase

Phosphorylates and activates MAP2K4 and MAP2K6| which in turn activate the JNK and p38 MAP kinases| respectively

resulting in stimulation of polymerase activity by enhancing DNA binding and processivity

This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors

MCAD Polyclonal Antibody, 100ul Sample Library Tubes Promotes endocytosis| possesses opsonic propertiesACADM encodes the medium chain specific (C4 to C12 straight chain) acyl Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta oxidation pathway. Defects in this gene cause medium chain acyl CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants

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