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PI4KA Rabbit Polyclonal Antibody, 100ul CellSafe™ 2004 [PubMed 15175245])

SKU: 77569096850

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PI4KA Rabbit Polyclonal Antibody, 100ul CellSafe™ 2004 [PubMed 15175245])This gene encodes a phosphatidylinositol (PI) 4 kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4 5 bisphosphate. The mammalian PI 4 kinases have been classified into two types II and III based on their molecular mass and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine.

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Description

2004 [PubMed 15175245])

Two transcript variants encoding different isoforms have been found for CCNC

in its inactive form

the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF

Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L)

PI4KA Rabbit Polyclonal Antibody, 100ul CellSafe™ 2004 [PubMed 15175245])This gene encodes a phosphatidylinositol (PI) 4 kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4 5 bisphosphate. The mammalian PI 4 kinases have been classified into two types II and III based on their molecular mass and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine.

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