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Originally developed for type 2 diabetes, these medications have emerged as powerful tools in the battle against excess weight

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Counterfeit and illegal products in circulation The FDA is also warning about counterfeit versions of drugs such as Ozempic being sold in the United States

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In contrast, selective inhibitors targeting each enzyme can block its activity at defined time points and in a dose-dependent manner, enabling more refined experimental control

Remarkably, carnosine, a naturally occurring dipeptide composed of -alanine and L-histidine, was identified as a consistently downregulated metabolite in both models ( Mechanistically, our in vitro data revealed that carnosine not only suppressed LPS-induced cytokine production in BMDMs but also inhibited their polarization toward the M1-like pro-inflammatory phenotype, which is known to exacerbate lung tissue damage (Yan et al., 2024