FAN Rabbit Polyclonal Antibody, 50ul Pathway and Network Analysis Two similar genes are located

Two similar genes are located nearby on chromosome 7q22 and a pseudogene is found on chromosome 7p13

and represses their transcriptional activity

NCOA4 encodes an androgen receptor coactivator

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control

Our sequences are in agreement with HGNC nomenclature

FAN Rabbit Polyclonal Antibody, 50ul Pathway and Network Analysis Two similar genes are locatedThis gene encodes a WD repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF mediated activation of neutral sphingomyelinase and may play a role in regulating TNF induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.