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Cells were then treated (duplicate wells/treatment) with stuarosporine (1 M) for 24 h [21] or H 2 O 2 (1002500 M, Sigma-Aldrich) for 2 h at 37 C a 30 min pre-treatment with inhibitors of cell death: liproxstatin (LPX, 10 M, Sigma-Aldrich) and necrostatin-1 (25 M) [22]

For those women, a lower dose isn't a diluted version of the real treatment

485 DOX can chelate Fe 3+ to form a complex with Fe 2+ , which triggers excessive lipid peroxidation within mitochondria, resulting in mitochondria-dependent ferroptosis

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Patients should avoid areas with active skin conditions, scars, moles, or recent sunburn