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Key points Metabolomic profiling in patients with systemic lupus erythematosus (SLE) has revealed substantial alterations in amino acid, lipid and energy metabolism, especially linked to oxidative stress and mitochondrial dysfunction, providing valuable indicators of disease activity and severity

Various efforts are made to achieve a positive pregnancy test

Glucagon-Like Peptide-1 7-36 Amide and Peptide YY from the L-Cell of the Ileal Mucosa Are Potent Inhibitors of Vagally Induced Gastric Acid Secretion in Man

Diet: Soluble fiber + protein + healthy fats 2

AOP Development Strategy Context This AOP was developed for the project "CHRONIC TOXICITY OF PESTICIDES IN DRINKING WATER IN PARABA (TRIGGER): IDENTIFYING THE TRIGGERS OF A SILENT EPIDEMIC," financed by the "Fundao de Apoio Pesquisa do Estado da Paraba (FAPESQ-PB)." The project aims to understand how oxidative stress and reproductive toxicity can be triggered in animals by aquatic pollutants, such as atrazine Strategy The first step in developing this AOP was to conduct a literature review to gather toxicological data on the herbicide atrazine's impact on aquatic vertebrates in relation to oxidative stress and reproductive toxicity

Journal of Pharmaceutical and Biomedical Analysis, 195, 113-126