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For instance, in cardiomyocytes, mitochondrial impairment may primarily disrupt energy production essential for cardiac contraction, while in neurons, it can lead to synaptic dysfunction and neurodegeneration [32]

Co-delivery nano system of MS-275 and V-9302 induces pyroptosis and enhances anti-tumor immunity against uveal melanoma

RNA-seq analysis revealed modulation of multiple genes associated with apoptosis, NF-B signaling, and metastasis suppression

Moreover, it has been reported that tetrahydrocurcumin reduces the levels of inducible NOS and cyclooxygenase-2 (COX-2) by downregulating extracellular signal regulated kinase 1/2 (ERK1/2) activation and has better activity than curcumin [122]

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